The process of change Becoming Pepsin pepsinogen - Tips Metabolism

By on 5:46 PM
The process of pepsinogen Being Pepsin
The process of change Becoming Pepsin pepsinogen - Tips Metabolism - Pepsinogen refers to pepsin which has not been active and is formed in the cells of the gastric mucous membrane.

Pepsinogen to be converted into pepsin autokatalisis manner with the aid of hydrochloric acid in the stomach.

Pepsin is a digestive enzyme in the stomach that functions to break down proteins into smaller particles.

Conversion process

Pepsinogen is secreted by cells in the gastric glands. Conversion of pepsinogen into pepsin is a relatively lengthy process.

For the conversion to occur, gastric pH should be below 4.5. Highly acidic conditions led to a number of changes in the structure of pepsinogen bond that eventually formed the enzyme pepsin.

Step in the Process of Conversion

A number of steps takes place during the conversion process. Initially, pepsinogen incubated with the so-called strong inhibitor pepstatin at pH 2.5.

These inhibitors have low molecular weights. The first protein resulting in activation then trapped in an inactive complex.

separation Association

Conversion of pepsinogen into pepsin involves a series of bond cleavage resulting in the removal of the prosegment or part of the amino acid at one end of the protein molecule.

use of Pepsin

Pepsin is a digestive enzyme that is critical in most mammals, including human stomach.

Pepsin ensure balance and regulation of normal protein digestion in the body. During digestion, proteins that have been digested and then into energy for the body.

Pepsin supplements also have benefits for dental health. Pepsin supplements in the form of pasta can be used to eliminate odors produced by the teeth and gums are exposed to infection.